Fatal neuroinflammation in a case of multiple sclerosis with anti-natalizumab antibodies.
نویسندگان
چکیده
منابع مشابه
Markers of JC virus infection in patients with multiple sclerosis under natalizumab therapy
OBJECTIVE To evaluate the frequency of JC polyomavirus (JCPyV) infection and anti-JCPyV antibodies in patients with multiple sclerosis under natalizumab therapy. METHODS Presence of anti-JCPyV antibodies and JCPyV DNA was analyzed in 39 patients with relapsing-remitting multiple sclerosis undergoing natalizumab therapy. Anti-JCPyV antibodies were evaluated in serum by a 2-step virus-like part...
متن کاملCase Reports: Ischemic Strokes in a Young Woman With Manifestations of Multiple Sclerosis
Background: The current case report aimed at describing the clinical, radiological, and immunological findings of a case of ischemic stroke due to acute thrombosis of the left internal carotid artery and multiple watershed infarctions mimicking Multiple Sclerosis (MS). Clinical Presentation and Intervention: A 24-year-old right-handed Iranian female was initially diagnosed with Multiple Sclero...
متن کاملClinical relevance of serum natalizumab concentration and anti-natalizumab antibodies in multiple sclerosis.
BACKGROUND Antibodies against natalizumab have been found in 4.5-14.1% of natalizumab-treated multiple sclerosis (MS) patients. If antibodies persist, they are associated with an adverse effect on treatment response. However, it has proved to be difficult to standardize anti-drug antibody measurements. OBJECTIVES The purpose of this study was to evaluate the clinical and radiological impact o...
متن کاملNeuromyelitis optica presenting with relapses under treatment with natalizumab: a case report
INTRODUCTION Neuromyelitis optica is an inflammatory demyelinating disease of the central nervous system. To date, optimal therapeutic approaches for neuromyelitis optica have yet to be defined. Natalizumab is highly effective in relapsing-remitting multiple sclerosis and might be considered as an option. CASE PRESENTATION Here, we describe a 67-year-old Caucasian man with definite neuromyeli...
متن کاملA challenging entity: multiple sclerosis or collagen tissue disorders: A case series of 6 patients
Background: Multiple sclerosis and other demyelinating processes are sometimes difficult to differentiate from the neurological involvement in autoimmune diseases. Distinguishing multiple sclerosis from other lesions due to autoimmune diseases is crucial to avoid unsuitable or delayed treatments. Methods: Charts of 6 patients diagnosed with mimicking multiple sclerosis between 1996 and 2014 we...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Neurology
دوره 80 10 شماره
صفحات -
تاریخ انتشار 2013